About Genome-Shield
Genome Shield in collaboration with scientists from leading universities in the US have developed a fast, effective and affordable test
called the Genome Shield iPGX Test. This test helps you determine the right drug and its dosage to reduce adverse drug reactions and
improve drug efficacy.
List of supporting evidence includes expert guidelines developed by the CPIC, DPWG,FDA and other professional societies. The drug
gene pairs indicated by PharmGKB in the column titled source have weaker evidence but still clinical literature backing it.
Methodology and Limitations
Genotyping based mass spectroscopy based assay detects all clinically significant alleles at analytical sensitivity and
specificity of 100%. The test does not include all possible variations in the individual tested. It may not detect all variations
that result in altered or inactive genes. Even if tested detectable mutations are absent, this does not imply that the patient
does not have other different phenotypes resulting from from other undetected genetic polymorphisms. At the time of
generation of the report the content is believed to be current based on published research. However research data evolves
and the prescription information could potentially change with time. Some of the interpretations provided in the report are
based on pharmacokinetic, pharmacodynamic and pharmacognenomic properties of a drug from non-clinical studies,
including in vitro and animal studies. Findings from studies in a non-clinical settings or clinical studies involving healthy test
subjects are not necessarily indicative of clinical performance in a particular patient.
Disclaimer
Content provided here is general health information. The recommendations in this report are not a substitute for
professional medical advice, diagnosis or treatment. Pharmacogenomics advice provided here is one of multiple pieces of
information that can be used to guide therapeutic choice of a patient. It remains the the responsibility of physician to
determine the best course of treatment including when information provide in in the report here is used. Adherence to
guidelines does not assure successful treatment.